This article examines how migraines are influenced by both environmental and genetic factors. It has been found that there are certain variants that contribute to networks of molecular differences. So far, there are 180 different variants of either neuronal or vascular that all account for a slight increase in migraine risk. Other factors like high blood pressure and depression also play a role in the risk of migraines.
Having a migraine can be disabling to everyday tasks. It is a complex neurological disorder in which genes interact with the environment and themselves. More recent studies have concluded that there is a heritability of about 42%. There are different classes or “varieties” of migraines. Each of these varieties has a different genetic mutation in mitochondrial DNA that leads to an increase in susceptibility to migraine. Additionally, studies were done on the reactions between migraines and other diseases.
As of the last 15 years, there has been a lot of progress made on migraines and its genetics. In my opinion, due to the debilitating nature of migraines this research is very important and has even lead to research on the interconnectedness of other diseases. The technology we have today opens up a lot of opportunity to do more research and find more answers. It is eyeopening to consider all of the possible new developments in this research. Much more studies must be done but it is promising based on the amount of research and knowledge already found. In the future further studies need to be completed on the loci where the susceptibility to migraines is found and specifically on mapping these loci. Additionally more research needs to be done on the relationship between migraines and other diseases. All of this information could lead to better ways to treat and even prevent a migraine.
https://link.springer.com/article/10.1186/s10194-023-01547-8
https://www.tandfonline.com/doi/full/10.2147/NDT.S282562
This is interesting an I would love to see the progress of the research in the future. My mom suffers from migraines fairly often and she doesn't exactly know why despite her being in good health. Its interesting to know that there is a possibility that the migraines are caused by a genetic issue rather than anything else.
ReplyDeleteI have a strong feeling I inherited migraine, but I have never done much about it because I always believed it was just a headache. Now that i know it is more complex than just a "bad headache", maybe I can get that taken care of. Especially since there is a chance migraine is connected to other health issues
ReplyDelete