Using human genetics to improve safety assessment of therapeutics

 In Carss et al.'s (2022) work from the authors investigate how human genetic knowledge can improve the safety evaluation of novel medicines.Researchers are able to better forecast and reduce potential side effects, which leads to safer and more effective therapies, by incorporating genetic information into drug development processes.The researchers cover a range of methods and approaches for using genetic data by emphasizing how this strategy might improve risk assessment and treatment outcomes.A major breakthrough in personalized medicine and medication development has been made with the incorporation of genetics into safety screening.

Carss, K. J., Deaton, A. M., Alberto Del Rio-Espinola, Diogo, D., Fielden, M., Kulkarni, D. A., Moggs, J., Newham, P., Nelson, M. R., Sistare, F. D., Ward, L. D., & Yuan, J. (2022). Using human genetics to improve safety assessment of therapeutics. 22(2), 145–162. https://doi.org/10.1038/s41573-022-00561-w