A new test has reported that the hearing of five deaf children has been restored using gene therapy. The children were all born with DFNB9, an inherited disease which is the result of mutations in the OTOF gene. The children received functioning versions of the OTOF gene via injections of a virus. In 2022 this gene therapy was proven to work when six patients received it and had some successful recovery of hearing. Although in both trials no side effects were observed, researchers believe that a second dose might cause a strong immune response.
This article goes to show how amazing modern medicine is! I wonder if this gene therapy can only be used on children or if this could be an option for adults too? So interesting to learn about all the ways we can modify our genes in case they are unfavorable like being deaf.
ReplyDeleteYou provided a fascinating and motivating overview of the most recent gene therapy research that aims to restore hearing to deaf children. It's amazing to see how a treatment that targets the underlying genetic cause of DFNB9 directly and provides significant benefits to those affected is being developed. While it is prudent to consider the potential risks associated with higher dosages, the initial efficacy and lack of reported adverse effects seem promising. This breakthrough highlights the potential applications of gene therapy to treat hereditary illnesses and improve patients' quality of life.
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