Saturday, February 17, 2024

Smoking Undermines Human DNA That Would Normally Prevent Cancer

Ernie Mundell reported the new research that was found from the Ontario Institute for Cancer Research that emphasized that smoking undermines human DNA that would normally prevent cancer. The research elaborated on how smoking prevents the formation of proteins that control cell development and leads to "stop-gain" mutations in cellular DNA, which prevent the body from producing protective proteins. The article also mentioned that tobacco does a lot of damage to our DNA and has a major impact on the function of our cells. When tobacco smoke enters the lungs, it triggers a dramatic influx of macrophages and neutrophils in the bronchi and pulmonary epithelia, and it triggers tumor development. The products in tobacco can alter the genome of immune cells, whether by implanting chemical adducts in the cellular DNA or by inducing irreversible genetic damage. 

I thought the article was insightful, especially when the reporter explained the reason why more stop-gain mutations can be found in tumors when a person smokes intensely and for a long period of time. I agree with the statement in the article that said, "Everyone knows smoking to be a major cause of cancer." However, I believe that not everyone knows how smoking can damage our DNA and mutations and how it can be prevented. 

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