In the article, “Genetic or Immune Defects May Impair Abilityto Fight Covid-19”, it demonstrates the severely ill patients from Covid-19 were more likely to carry a mutation that affects the making of the type 1 interferon. This type 1 interferon is a frontline immune molecule and helps fight off illnesses as soon as detected. Another study mentioned, showed patients carrying antibodies to their own interferon. This was not found in the asymptomatic people. This would mean they destroy their own interferon. I believe there is a lot to still understand about COVID-19 and finding out this mutation did help understand why COVID-19 affects people differently. Finding out one reason why COVID-19 affects people different is a step in the right direction. This article provided information that I believe will help provide a stepping stone to understand the different affects of COVID-19 on different people.
Additional link: https://www.covidhge.com/about