Genetic Explanation for African American Susceptibly to Cancer
AfricanAmericans tend to have a shorter survival period and higher death rates amongst
other races when it comes to cancer. Researchers have studied socioeconomic
factors to find an explanation. Others studied the genetic component. A single
variant is the explanation. The variant have never been observed in Caucasian
people. This variant can be crucial for providing improved prognosis and treatment
that will result in lower death rates.
In finding the variant, researchers focused on a tumorsuppressor gene that is mutated. This gene is activated in most cancers and
only occurs in people of African decent. About 2-8% of African and African
Americans have this mutation. The researchers tested the variant on mice and
80% of those mice developed cancer. The types of cancer in which the mice
developed were the common cancers found in African Americans.
This
finding it truly life-saving! Now that scientists have isolated the mutated
gene, accurate prognoses can be given. Different races may have different genetic
explanations and these findings could start a revolution to finding the cure to
cancer.
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