A multinational research team has discovered an explosive cell
lysis mechanism of bacteria
controlled by a phage-related enzyme that releases cell-derived public goods
and is activated by stress. The researchers found that explosive cell lysis
also contributed to membrane vesicle formation, which helps determine bacterial
virulence. These findings further help understanding of how bacteria control
their environment and interact as communities. This could aid the development
of growth inhibition techniques. Researchers have been unclear on how bacteria
form and release certain extracellular components involved in cell adhesion and
multicellular structures that also contribute to antibiotic resistance.
However, a recent study from a multinational team of researchers identified a
previously unknown phenomenon, explosive cell lysis, as crucial in the
production of membrane vesicles and biofilm formation. Bacteria cells change
from a rod-like to spherical shape before exploding controlled by the Lys
enzyme. Cell membrane fragments curl up to form vesicles and extracellular DNA
are released, which can interact with other cells.
This
article
is absolutely amazing. This study will help to better membrane vesicle
formation which in turn will lead to earlier virulence determination in certain
bacteria. If we could determine specific bacterial influences before they even
happen we could better prepare for outbreaks and help to develop cures and
remedies earlier on. This would better our bacterial impact and help to lessen
symptoms in a larger population than ever before thanks to these studies. All
in all I believe this was a very well written article and it shines a light on the
extensiveness of this study and how revolutionary this research could truly be.
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