Thursday, March 19, 2015

New tool can switch behavior -- such as voracious eating -- 'on' and 'off'

A new chemogenetic technique can now be used to control voracious eating within mice.  This technique can be used as an on or off switch that control a certain behavior by targeting the cell surface of receptors for neurons and either enabling or inhibiting a certain receptor.  Neuron receptors are responsible for sending signals throughout the nervous system.  This is a delicate system and even the slightest error within this system can lead to epilepsy, schizophrenia, depression or even Alzheimer's disease.  This new chemogenetic tool can change the shape of a neuroreceptor and allow only a certain signal to be sent through.  This may lead to a better understanding of the neurological system.  Although, it is unclear how to change certain receptors to control different neurological impulses.  More studies are being done to determine an "on and off switch" for certain behaviors.  This study will hopefully shine light on therapeutic uses.
http://www.sciencedaily.com/releases/2015/04/150430124000.htm
I had some initial concerns when I was first reading this article.  I know that the neurological system is a highly sensitive system and there is still a lot to learn about it.  Although this therapy is effective on changing a certain behavior, you can't help but wonder what the long term effects of this chemogenetic technique can be for this nervous system.  If the long term effects are better understood, this may lead to breakthroughs in treating schizophrenia and or any dangerous neurological problems.  This can also lead to therapy for drug related issues.

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