Saturday, April 14, 2012

Uncrossing chromosomes

In this article, researchers at the University of California, Davis have come across enzymes that work with the crossing over in chromosomes.  This is a very important part of meiosis to create differentiation in cells, it could also result in mutations that end in diseases or death.  Neil Hunter, a professor of microbiology at UC Davis, has been the one working on a lot of this research.  The main reason for the research is to find the missing tool that regulates crossing over so that there is cross over but not too many.  Though there were many good candidates there were unable to find something.  While using yeast to do this experiment, they did, however, come across enzymes Mlh1, Mlh3 and Sgs1, which work together to cut DNA and make crossovers.  it turned out that the enzymes they foud in the yeast has human equivalence to certain cancers.  if this is what was found, the future of cancer research could be getting the help.   With more research the hope to is this newly found knowledge and the issues with cancer could be a huge break through.

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