Previously believed to be caused purely by stress, emotions, and depression, migraines are now believed to have over 40 genes that can trigger the onset of a debilitating migraine, sometimes also being accompanied by nausea, blind spots, flu-like symptoms, disorientation, and trouble thinking. Specifically, calcitonin, which is a gene-related peptide abundantly found in people who tend to receive migraines more often than others, is being studied and tested to find a cure. This peptide produces the swelling of blood vessels within the brain, ultimately resulting in a migraine to form. In fact, about 50% of the people who develop severe migraines is due to their genetic predisposition.
While there are genes that enable migraines to form, they can also be triggered by by external factors, possibly smells, alcohol, specific foods, lights, and especially noises, that takes a normal headache to the next level. When this occurs, it could last anywhere from 4 hours to four days. It is when these outside factors become so extremely amplified within the brain and activates the neural networks, causing a very painful migraine.
As technology improves and scientists are able to better distinguish which specific genes are directly linked to the development of severe migraines, new forms of medication could possibly be made. I think it will be able to provide an entirely new lifestyle change to people afflicted and look forward to cures being fabricated, especially as someone who oftentimes get migraines.