The international study looked at DNA from more than 26,000 people found several genetic vari
ants that substantially increase susceptibility to asthma a (chronic long-term lung disease that inflames and narrows the airways) in children. Most importantly, the study appears to show that allergies are a ‘side effect’ of asthma, rather than causing the condition. Researchers analysed DNA samples from 10,000 children and adults with asthma and 16,000 non-asthmatics. The researchers performed more than half a million genetic tests on each subject, covering all the genes in the human genome. The study pinpointed seven locations on the genome where differences in the genetic code were associated with asthma. Some of the genes identified are involved in signalling pathways that tell the immune system when the lining of the airways has been damaged. Other genes appear to control how quickly the airways heal after they have been injured.Allergies have always been closely correlated with asthma. It has been believed that allergies cause the onset of asthma because they can
cause damage to air-pathways. Through the findings from this research, it has been proven that genetics has a role in the disease. Now that they have identified seven genes in connection with asthma, they can target their research to develop treatments that effectively treat the allergies associated with asthma, as well as the genes that play a role in the disease. The results from this research will now help to ensure that scientists are able to focus their research on the most influential targets for asthma, with the important long-term aim of preventing a condition which is responsible for the death of three people every day. The two treatments today for asthma are 1. long-term medications to prevent asthma attacks and 2. quick-relief medication for use during asthma attacks. I hope they can develop more effective treatments in the very near future and they can develop a prevention system so many people do not have to suffer with this disease.Find out more information about asthma at: https://health.google.com/health/ref/Asthma
When I read this article I thought about myself because I am pre-asthmatic. Thankfully I have recovered from this illness. I wish they had found out this study before when I was ill, but I am glad that they have found it now. It will help other patients understand this disease better. However, even from the start I believed that asthma was genetically caused because my grandmother had it. I hope they find more treatments for this disease because BELIEVE ME, it is NOT a breath of fresh air! ;)
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