Saturday, November 27, 2010

New Function of Gene In Promoting Cancer

Researchers at Virginia Commonwealth University have discovered that the gene, AEG-1, contributes in tumor cell development, growth, and chemotherapeutic drug resistance by regulating diverse intracellular processes.  Studies have revealed a previously unknown function of AEG-1 by indentifying the gene as a potential regulator of protective autophagy.  This protective autophagy shields cancer cells from destructive agents, such as chemotherapy.  It may also contribute to AEG-1's tumor-promoting properties.

By understanding how this gene promotes resistance to chemotherapy and contributes to cancer cell survival, researchers may discover new treatments that can regulate the AEG-1 gene.  This discovery will hopefully lead to other drugs and beneficial approaches for cancers that are difficult to treat because of resistance to current therapies.

2 comments:

  1. This article caught my eye because it always makes me hopeful to see possible advancements in cancer therapies. I have known several people who have had to undergo cancer treatments, and the possibility that these treatments may become more effective because of this knowledge is certainly something that can make one optimistic.

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  2. This is so great. I'm always all for anything that can benefit cancer in the end, so this article is definitely a good chance for hope with it. Let's hope it does end up benefiting all it can!

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