Wednesday, April 3, 2019
Coffee dependence and Genetics?
Some people heavily rely on their morning coffee to start their day, while others avoid coffee. The dependence on caffeine could be because of our genes - in particular the CYP1A2 gene. This gene is in charge of the CYP1A2 enzyme which is responsible for breaking down caffeine in the body. The gene expresses a slow metabolizer or a fast metabolizer. A study showed that a slow metabolizer could drink 4 cups of coffee and be linked to a higher chance of a heart attack, but a fast metabolizer could drink the same amount and not have any link to a higher chance of a heart attack.
Another gene that can also be accountable for how much coffee an individual consumes is the AHR gene. The gene controls how much of CYP1A2 enzyme are produced. The more CYP1A2 enzymes are produced the faster caffeine is metabolized in the body which will then increase the amount of coffee an individual drinks.