New Test Can Predict a Man's Sexual Orientation

Researchers have recently developed a test that is said to be able to predict a man's sexuality with up to 70% accuracy. The test uses an algorithm that can identify patterns of DNA methylation, a molecular modification to DNA that controls gene expression, across nine regions of the human genome that researchers believe might be related to sexual orientation. DNA methylation occurs as a result of environmental factors, such as exposure to chemicals, stress, diet, and exercise.

The recent study of the process builds upon previous studies that have shown that a person's sexuality may be determined by the activity of certain genes and that epigenetic differences are one of the main reasons that identical twins who share all their genes can vary in homosexuality. In the study the team of researchers employed 37 pairs of identical male twins, where one was homosexual and one was heterosexual, and another 10 pairs, where both males were homosexual. They were then capable of pinpointing specific DNA methylation patterns that might be associated with sexual orientation utilizing an algorithm called FuzzyForest. From this, the researchers were able to identify these DNA methylation patterns in 9 specific areas of the human genome that could determine each twins sexuality with 70% accuracy. These areas were capable of being defined to the base pair level.

The researchers now say they are unable to explain how the DNA methylation in these specific areas of the human genome can actually influence a man's sexuality, but they plan to address the concept in further studies. Meanwhile, they will continue to test the accuracy of the algorithm in a larger population of men.

I find this study very interesting. Given that the genetic and molecular basis of our sexual orientation is not well known, the study is a huge step in helping us understand ourselves and why we are the way we are.

For a link the the actual article click here
For more articles on this study click here